Re-Engagement of Patients with Hepatitis C in the Context of COVID-19
DOI:
https://doi.org/10.52787/agl.v52i1.180Keywords:
Hepatitis C, re-engagement, pandemic, cirrhosis, loss to follow-upAbstract
Hepatitis C virus infection is one of the main causes of morbidity and mortality worldwide. In Argentina, it is estimated that only 50% of infected people are diagnosed; of these, half have confirmed their diagnosis, and only 5% have access to treatment.
The COVID-19 pandemic has exacerbated this situation, further decreasing access to treatment. In this context, we developed a program to reconnect and simplify the patient care cascade, in order to facilitate access to diagnosis, treatment, and monitoring of complications associated with hepatitis C virus infection.
24.2% of the re-engaged patients were candidates for treatment, and they received it in only 2 medical consultations, with an average time of 29 days between the initial consultation and the delivery of the medication. The results of our study show that approximately half of the patients with hepatitis C are not followed up by a specialist. Of the patients who had cirrhosis at the time of re-engagement, 60% had mild fibrosis prior to admission to the program. More than 80% of patients with cirrhosis could not be re-engaged. A commitment from the healthcare team is required to facilitate the reduction of the instances necessary to access treatment, and programs focused on education and assessment of the patient's psychosocial environment. This will make it possible to break down existing barriers.
References
- 1. Guía para el diagnóstico y tratamiento de la infección por el virus de las hepatitis B y C. Argentina 2021. Ministerio de Salud 2021.
- 2. Dirección de Respuesta al VIH, ITS, Hepatitis Virales y Tuberculosis Argentina. Boletín N.º 3: Hepatitis virales en la Argentina: Año III - Diciembre 2021.
- 3. World Health Organization, Global Health Sector Strategy on Viral Hepatitis 2016-2021: Towards Ending Viral Hepatitis. 2016;6:1-56. Disponible en: http://www.who.int/hepatitis/strategy2016-2021/ghss-hep/en/
- 4. Cooke GS, Andrieux-Meyer I, Applegate TL, et al. Accelerating the elimination of viral hepatitis: a Lancet Gastroenterology & Hepatology Commission. Lancet Gastroenterol Hepatol. 2019;4:135-84.
- 5. Wingrove C, James C, Wang S. The impact of COVID-19 on hepatitis services and civil society organisations. Lancet Gastroenterol Hepatol. 2021;6:682-4.
- 6. EASL Recomendations on Treatment of Hepatitis C: final update of the series. J Hepatol. 2020. doi: https://doi.org/10.1016/j.jhep.2020.08.018
- 7. SAHE. Recomendaciones para el Tratamiento de la Hepatitis Crónica por Virus C: Actualización 2020.
- 8. Yoshiji H, Nagoshi S, Akahane T, et al. Evidence-based clinical practice guidelines for Liver Cirrhosis 2020. J Gastroenterol. 2021;56(7):593-619. doi: 10.1007/s00535-021-01788-x
- 9. Mendizábal M, et al. Efectividad de una estrategia de revinculación al cuidado de pacientes con hepatitis C previamente perdidos de seguimiento. ALEH. Marzo 2020.
- 10. Kracht PAM, et al. Retrieval and cure of chronic hepatitis C (REACH): results of micro-elimination in the Utrecht province. Liver Int. 2019;39(3):455-62. doi: 10.1111/liv.13959
- 11. Beekmans N, Klemt-Kropp M. Re-evaluation of chronic hepatitis B and hepatitis C patients lost to follow-up: results of the Northern Holland hepatitis retrieval project. Hepatol Med Policy. 2018;3:5. doi: 10.1186/s41124-018-0032-9
- 12. Heil J, et al. Retrieval and re-evaluation of previously diagnosed chronic hepatitis C infections lost to medical follow-up in the Netherlands. Eur J Gastroenterol Hepatol. 2020;32(7):851-6. doi: 10.1097/MEG.0000000000001593
- 13. Yen HH, Su PY, Liu II, et al. Retrieval of lost patients in the system for hepatitis C microelimination: a single-center retrospective study. BMC Gastroenterol. 2021;21(1):209. doi: 10.1186/s12876-021-01792-8
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Gisela Fabiana Sotera, Melina Ferreiro, Margarita Martes, Nancy Cordero, Jonathan Salmon, Juan Sordá, Jorge Daruich, Esteban González Ballerga

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.










