Teduglutida en pacientes adultos con falla intestinal crónica por síndrome de intestino corto: protocolo de manejo con base en recomendaciones de expertos
DOI:
https://doi.org/10.52787/agl.v52i1.168Palabras clave:
Falla intestinal tipo III, falla intestinal crónica, síndrome de intestino corto, nutrición parenteral, enterohormonas, GLP2, rehabilitación intestinal, trasplante de intestino, teduglutidaResumen
La falla intestinal crónica por síndrome de intestino corto es una patología severa y compleja que requiere un abordaje multidisciplinario especializado. La nutrición parenteral es el soporte fundamental en estos pacientes, aunque, a largo plazo, pueden desarrollarse complicaciones asociadas a esta que contraindiquen su continuidad. En este contexto, el trasplante de intestino aislado o combinado (intestino-hígado) es la última alternativa para recuperar la suficiencia intestinal. A partir del año 2012, se introdujo en el mundo el uso del péptido semisintético de GLP-2, denominado Teduglutida, que cambió el curso y el pronóstico de esta patología. La Argentina es el país de Latinoamérica con mayor experiencia en el uso de esta enterohormona, con resultados comparables a los de otros centros internacionales. Este artículo resume las recomendaciones de expertos para el uso de Teduglutida en pacientes portadores de falla intestinal crónica por síndrome de intestino corto.
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Derechos de autor 2022 Héctor Solar, Adriana Crivelli, Silvia de Barrio, Martin Buncuga, Alejandra Manzur
Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-CompartirIgual 4.0.
