Cephalic Duodenopancreatectomy in Patients with Locally Advanced Right Colon Cancer
DOI:
https://doi.org/10.52787/agl.v53i2.325Keywords:
En bloc resection, locally advanced colon cancer, pancreatoduodenectomy, colectomyAbstract
Introduction. Locally advanced colon cancer represents 5% to 22% of the total. In patients with right colon cancer and invasion of the pancreas and/or duodenum the recommended surgery is en bloc resection. However, the morbidity and mortality associated with this procedure may condition the decision-making regarding the choice of treatment.
Aim. To analyze the results of en bloc resections in patients with locally advanced right-sided colon cancer with duodenal and/or pancreatic infiltration in a referral center.
Materials and methods. A retrospective descriptive analysis of patients with right colon cancer with infiltration to the duodenum and/or pancreatic head, evaluated between November 2013 and November 2019, who underwent en bloc resection with cephalic duodenopancreatectomy.
Results. Seven patients with locally advanced colon cancer included studied. 42,85% (n= 3) had tumor infiltration into the duodenum, while 42.85% (n= 3) infiltrated the duodenum and pancreatic head and 14.28% (n= 1) did not infiltrate structures. The disease-free period was 41.93 months (12-95) and 28.57% (n= 2) of patients had disease recurrence.
Conclusions. Patients with locally advanced right colon cancer undergoing duodenopancreatectomy, regardless of the size and tumor infiltration, have a high morbidity and mortality rate as a consequence of surgery. However, the procedure offers a favorable longterm survival.
References
-1. Akkoca AN, Yanık S, Ozdemir ZT, Cihan FG, Sayar S, Cincin TG, et al. TNM and Modified Dukes staging along with the demographic characteristics of patients with colorectal carcinoma. Int J Clin Exp Med [Internet]. 2014;7(9):2828-35. PMID: 25356145; PMCID: PMC4211795.
-2. Fuks D, Pessaux P, Tuech JJ, Mauvais F, Bréhant O, Dumont F, et al. Management of patients with carcinoma of the right colon invading the duodenum or pancreatic head. Int J Colorectal Dis [Internet]. 2008;23(5):477-81. DOI:10.1007/s00384-007-0409-5
-3. Ağalar C, Canda AE, Unek T, Sokmen S. En Bloc Pancreaticoduodenectomy for Locally Advanced Right Colon Cancers. Int J Surg Oncol [Internet]. 2017;5179686. DOI:10.1155/2017/5179686
-4. Cirocchi R, Partelli S, Castellani E, Renzi C, Parisi A, Noya G, et al. Right hemicolectomy plus pancreaticoduodenectomy vs partial duodenectomy in treatment of locally advanced right colon cancer invading pancreas and/or only duodenum. Surg Oncol [Internet]. 2014;23(2):92-8. DOI:10.1016/j.suronc. 2014.03.003
-5. Saiura A, Yamamoto J, Ueno M, Koga R, Seki M, Kokudo N. Long-term survival in patients with locally advanced colon cancer after en bloc pancreaticoduodenectomy and colectomy. Dis Colon Rectum [Internet]. 2008;51(10):1548-51. DOI:10.1007/s10350-008-9318-0
-6. Marsman EM, de Rooij T, Van Eijck CH, Boerma D, Bonsing BA, Van Dam RM, et al. Pancreatoduodenectomy with colon resection for cancer: A nationwide retrospective analysis. Surgery [Internet]. 2016;160(1):145-52. DOI:10.1016/j.surg.2016.02.022
-7. Koea JB, Conlon K, Paty PB, Guillem JG, Cohen AM. Pancreatic or duodenal resection or both for advanced carcinoma of the right colon: is it justified? Dis Colon Rectum [Internet]. 2000;43(4):460-5. DOI:10.1007/BF02237187
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Gerardo Miranda Devora, Horacio Noé López-Basave, Flavia Morales-Vásquez, Angel Herrera-Gómez, Carolina Castillo-Morales, Alejandro Eduardo Padilla-Rosciano
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
