Prevalence of Helicobacter pylori in Obese Patients Undergoing Bariatric Surgery in a Hospital in Argentina

Authors

  • Leonardo García Allende Servicio de Gastroenterología y Endoscopía Digestiva. Hospital Privado de Comunidad, Mar del Plata, Buenos Aires, Argentina. https://orcid.org/0009-0007-0980-0716
  • Jorge Laborda Molteni Servicio de Gastroenterología y Endoscopía Digestiva. Hospital Privado de Comunidad, Mar del Plata, Buenos Aires, Argentina.
  • Nora Fuentes Departamento de Investigación. Hospital Privado de Comunidad, Mar del Plata, Buenos Aires, Argentina.
  • Eugenio Federico Tonn Servicio de Gastroenterología y Endoscopía Digestiva. Hospital Privado de Comunidad, Mar del Plata, Buenos Aires, Argentina.

DOI:

https://doi.org/10.52787/agl.v54i2.400

Keywords:

Helicobacter pylori, obese patients, bariatric surgery

Abstract

Bariatric surgery is indicated in patients with morbid grade III obesity or grade II obesity with associated comorbidities. Helicobacter pylori is a bacterium that can adapt to gastric acidity, and obtain a micro niche for permanent colonization. The Argentine Consensus on Nutrition in Bariatric Surgery recommended upper gastrointestinal endoscopy with evaluation of H. pylori before bariatric surgery. This research aimed to determine the prevalence of H. pylori and associated factors in patients with grade II and III obesity undergoing bariatric surgery at the Private Community Hospital of the city of Mar del Plata between January 2015 and December 2019. The study was cross-sectional on a cohort of patients undergoing bariatric surgery at the hospital, through a retrospective review of computerized medical records. Patients between 18 and 75 years old, of both sexes, were included. Data were analyzed with STATA 15.1. The study population consisted of 262 patients; 71% were female. The median age was 42.5 years and the median body mass index was 42.4 kg/m2. H. pylori was detected in gastric biopsies in 40% of patients. H. pylori was detected in 40.2% of patients with normal endoscopy. The most frequent endoscopic pattern in patients undergoing bariatric surgery was gastropathy; the prevalent histological finding was chronic gastritis and was the only variable associated with the presence of H. pylori.

References

-1. Omer T. The causes of obesity: an in-depth review. Adv Obes Weight Manag Control 2020;10(3):90-94.

-2. Purnell JQ. Definitions, Classification, and Epidemiology of Obesity. [Updated 2023 May 4]. In: Feingold KR, Anawalt B, Blackman MR, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK279167/

-3. Instituto Nacional de Estadísticas y Censos, República Argentina (INDEC). 4° Encuesta Nacional de Factores de Riesgo. Resultados definitivos. - 1a ed. - Ciudad Autónoma de Buenos Aires: Instituto Nacional de Estadística y Censos - INDEC; Ciudad Autónoma de Buenos Aires: Secretaría de Gobierno de Salud de la Nación, 2019. Disponible en: https://www.indec.gob.ar/ftp/cuadros/publicaciones/enfr_2018_resultados_definitivos.pdf

-4. Harraca DJL, Grigaites DAL, Martínez Duartez P, Aguirre Ackermann M, Quevedo P, Musso C, Fuentes S, Salmeri E, Calderón G, Roussos A, Farías JM, Ferraro AA, Bocanera L, Lerner M, Babor E, Fernández E, Deluca L, Gorodner V. Consenso Argentino Intersociedades de Cirugía Bariátrica y Metabólica. Rev Arg Cir. 2021; 113 (Supl 1): 1-70. Retrieved from https://revista.aac.org.ar/index.php/RevArgentCirug/article/view/179

-5. Hooi JKY, Lai WY, Ng WK, Suen MMY, Underwood FE, Tanyingoh D, Malfertheiner P, Graham DY, Wong VWS, Wu JCY, Chan FKL, Sung JJY, Kaplan GG, Ng SC. Global Prevalence of Helicobacter pylori Infection: Systematic Review and Meta-Analysis. Gastroenterology. 2017; 153(2):420-429.

-6. Hunt RH, Xiao SD, Megraud F, Leon-Barua R, Bazzoli F, van der Merwe S, Vaz Coelho LG, Fock M, Fedail S, Cohen H, Malfertheiner P, Vakil N, Hamid S, Goh KL, Wong BC, Krabshuis J, Le Mair A; World Gastroenterology Organization. Helicobacter pylori in developing countries. World Gastroenterology Organisation Global Guideline. J Gastrointestin Liver Dis. 2011 20(3):299-304.

-7. Dixon MF, Genta RM, Yardley JH, Correa P. Classification and grading of gastritis. The updated Sydney System. International Workshop on the Histopathology of Gastritis, Houston 1994. Am J SurgPathol. 1996; 20(10):1161-181.

-8. Rugge M, Correa P, Di Mario F, et al. OLGA staging for gastritis: a tutorial. Dig Liver Dis. 2008; 40: 650-658.

-9. Pajares García JM. Infección por Helicobacter pylori. Rev Clin Esp 2002; 202(2):99-110.

-10. Otero W, Otero L, Trespalacios AA. Helicobacter pylori y alteraciones endoscópicas en pacientes con obesidad severe, programados para cirugía bariátrica. Rev Col Gastroenterol 2015;30(2):165-1.

-11. Dietz J, Ulbrich-Kulcynski JM, Souto KE, Meinhardt NG. Prevalence of upper digestive endoscopy and gastric histopathology findings in morbidly obese patients. ArqGastroenterol. 2012;49(1):52-55.

-12. Laudanno O, Thome M, Ahumarán G, Gollo P, González P, Mastruzzo M. Preoperative upper endoscopy in asymptomatic obese patients undergoing bariatric surgery: is it mandatory? Gastrointestinal endoscopy. 2019; 89:554-5.

-13. Küper MA, Kratt T, Kramer KM, Zdichavsky M, Schneider JH, Glatzle J, Stüker D, Königsrainer A, Brücher BL. Effort, safety, and findings of routine preoperative endoscopic evaluation of morbidly obese patients undergoing bariatric surgery. Surg Endosc. 2010; 24(8):1996-2001.

-14. Olmos JA, Ríos H, Higa R, the Argentinean Hp Epidemiologic Study Group. Prevalence of Helicobacter pylori Infection in Argentina: Results of a Nationwide Epidemiologic Study. J Clin Gastroenterol 2000; 31(1): 33-37.

-15. Zhang Y, Du T, Chen X, Yu L, Zhang C. Association between Helicobacter pylori infection and overweight or obesity in a Chinese population. J Infect Dev Ctries 2015; 9(9):945-953.

-16. Redéen S, Petersson F, Jönsson KA, et al. Relationship of gastroscopic features to histological findings in gastritis and Helicobacter pylori infection in a general population sample. Endoscopy 2003;35(11):946-50.

-17. Schlottmann F, Sadava EE, Reino R, Galvarini M, Buxhoeveden R. Preoperative endoscopy in bariatric patients may change surgical strategy. Acta Gastroenterol Latinoam 2017;47(2):117-121.

-18. Al-Akwaa AM, Ahmad M. Prevalence of Helicobacter pylori Infection in a group of morbidly obese Saudi patients undergoing bariatric surgery: A preliminary report. Saudi J Gastroenterol 2010;16(4):264-267.

-19. Renshaw AA, Rabaza JR, Gonzalez AM, Verdeja JC. Helicobacter pylori infection in patients undergoing gastric bypass surgery for morbid obesity. Obes Surg. 2001;11(3):281-283.

-20. Burgos L Ana María, Csendes J Attila, Braghetto M Italo, Muñoz Ch Andrea, Villanueva I María. Hallazgos histológicos gástricos en obesos mórbidos sometidos a gastrectomía vertical laparoscópica. RevChilCir 2014;66(3):224-230.

-21. Evans J, Muthusamy V, Acosta D, Bruining D, Chandrasekhara V, Chathadi K, Eloubeidi M, Fanelli R, Faulx A, Fonkalsrud L, Khashab M, Lightdale J, Pasha S, Saltzman J, Shaukat A, Wang A, Stefanidis D, Richardson W, Kothari S, Cash B, American Society for Gastrointestinal Endoscopy Standards of Practice Committee. The role of endoscopy in the bariatric surgery patient. Gastrointestinal Endoscopy 2015; 81:1063-1072.

-22. Pampillón N, Reynoso C, Pagano C. Consenso Argentino de Nutrición en Cirugía Bariátrica. Actualización en Nutrición 2012; 12: 98-141.

-23. Pampillón N, Reynoso C, Solimano M. Actualización del Consenso Argentino de Nutrición en Cirugía Bariátrica. Actualización en Nutrición 2016;17:19-32.

Published

2024-07-01

How to Cite

García Allende, L., Laborda Molteni, J., Fuentes, N., & Tonn, E. F. (2024). Prevalence of Helicobacter pylori in Obese Patients Undergoing Bariatric Surgery in a Hospital in Argentina. Acta Gastroenterológica Latinoamericana, 54(2), 153–159. https://doi.org/10.52787/agl.v54i2.400