Novedades terapéuticas en la esofagitis eosinofílica

Autores/as

  • Javier Molina-Infante Servicio de Aparato Digestivo, Hospital Universitario de Cáceres, Cáceres, España. https://orcid.org/0000-0003-1204-0571
  • Alfredo J Lucendo Centro de Investigación Biomédica en Red Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, España https://orcid.org/0000-0003-1183-1072

DOI:

https://doi.org/10.52787/agl.v52i4.270

Palabras clave:

Esofagitis eosinofílica, inhibidor de la bomba de protones, corticoides tópicos, dieta, fármacos biológicos, dilatación

Resumen

La esofagitis eosinofílica (EoE) es una enfermedad inmunoalérgica crónica causada, en la mayoría de los casos, por una alergia alimentaria no IgE mediada. Su prevalencia actual es superior a 1 caso por cada 1000 habitantes en España y Europa, mientras que es emergente en el continente sudamericano. Esta revisión trata de actualizar las novedades terapéuticas aparecidas en los últimos 5 años para inducción y mantenimiento en esta patología, incluyendo la aparición de nuevos fármacos antiácidos (inhibidores del ácido competitivos del potasio), la simplificación de los esquemas dietéticos, la aparición de nuevos corticoides deglutidos diseñados específicamente para el tratamiento tópico, así como la incorporación de fármacos biológicos al algoritmo terapéutico de la enfermedad. La dilatación endoscópica continúa siendo un complemento eficaz y seguro para la mejoría sintomática, en combinación con tratamientos antiinflamatorios de la enfermedad.

Citas

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2022-12-21

Cómo citar

Molina-Infante, J., & Lucendo, A. J. (2022). Novedades terapéuticas en la esofagitis eosinofílica. Acta Gastroenterológica Latinoamericana, 52(4), 439–452. https://doi.org/10.52787/agl.v52i4.270