Diagnostic Imaging in the Developmental Anomalies of the Pancreas
DOI:
https://doi.org/10.52787/agl.v55i1.462Keywords:
Pancreas, developmental anomalies, pancreatic duct, computed tomography, magnetic resonance cholangiopancreatographyAbstract
Congenital anomalies of the pancreas result from failure of proper migration and/or fusion during embryologic development. They are usually diagnosed in adulthood, incidentally in imaging studies performed for other reasons. Some patients may develop symptoms such as abdominal pain or even relevant clinical conditions including gastric outflow tract obstruction, acute and recurrent pancreatitis. In this article we will review the imaging features of the most important congenital pancreatic anomalies, with emphasis on magnetic resonance cholangiopancreatography.
References
-1. Langman J, Sadler T. Medical embryology. 12th ed. Baltimore: Lippincott, Williams & Wilkins, 2020;220-222.
-2. Schulte SJ. Embryology, normal variation, and congenital anomalies of the pancreas. Margulis and Burhenne alimentary tract radiology. 5th ed. St Louis, Mo: Mosby, 1994;1039-1051.
-3. Rizzo RJ, Szucs RA, Turner MA. Congenital abnormalities of the pancreas and biliary tree in adults. Radiographics 1995;15(1),49-68.
-4. Borghei P, Sokhandon F, Shirkhoda A, Morgan D. Anomalies, anatomic variants, and sources of diagnostic pitfalls in pancreatic imaging. Radiology. 2013;266(1),28-36.
-5. Agha FP, Williams KD. Pancreas divisum: incidence, detection, and clinical significance. Am J Gastroenterol. 1987;82(4):315-20.
-6. Ferri V, Vicente E, Quijano Y, Ielpo B, Duran H, Diaz E, Caruso R. Diagnosis and treatment of pancreas divisum: A literature review. Hepatobiliary & Pancreatic Diseass International. 2019;18(4),332-336.
-7. Kim SS, Shin HC, Hwang JA. Various congenital abnormalities and anatomic variants of the pancreas: A pictorial review. Journal of the Belgian Society of Radiology. 2019;103(1).
-8. Bertin C, Pelletier AL, Vullierme MP, Bienvenu T, Rebours V, Hentic O, et al. Pancreas divisum is not a cause of pancreatitis by itself but acts as a partner of genetic mutations. Official journal of the American College of Gastroenterology ACG. 2012;107(2),311-317.
-9. Yu J, Turner MA, Fulcher AS, Halvorsen RA. Congenital anomalies and normal variants of the pancreaticobiliary tract and the pancreas in adults: part 2, pancreatic duct and pancreas. American Journal of Roentgenology. 2006;187(6),1544-1553.
-10. Eisen G, Schutz S, Metzler D, Baillie J, Cotton PB. Santorinicele: new evidence for obstruction in pancreas divisum. Gastrointestinal endoscopy. 1994;40(1),73-76.
-11. Türkvatan A, Erden A, Türkoğlu MA, Yener Ö. Congenital variants and anomalies of the pancreas and pancreatic duct: imaging by magnetic resonance cholangiopancreaticography and multidetector computed tomography. Korean journal of radiology. 2013;14(6),905-913.
-12. Manfredi R, Costamagna G, Brizi MG, Spina S, Maresca G, Vecchioli A, et al. Pancreas divisum and “santorinicele”: diagnosis with dynamic MR cholangiopancreatography with secretin stimulation. Radiology. 2000;217(2),403-408.
-13. Bret PM, Reinhold C, Taourel P, Guibaud L, Atri M, Barkun AN. Pancreas divisum: evaluation with MR cholangiopancreatography. Radiology. 1996;199(1),99-103.
-14.Misra SP, Gulati P, Thorat VK, Vij JC, Anand BS. Pancreaticobiliary ductal union in biliary diseases: an endoscopic retrograde cholangiopancreatographic study. Gastroenterology. 1989;96(3),907-912.
-15. Sugiyama M, Haradome H, Takahara T, Abe N, Tokuhara M, Masaki T, et al. Anomalous pancreaticobiliary junction shown on multidetector CT. American Journal of Roentgenology. 2003;180(1),173-175.
-16. Mortelé KJ, Rocha TC, Streeter JL, Taylor AJ. Multimodality imaging of pancreatic and biliary congenital anomalies. Radiographics. 2006;26(3), 715-731.
-17. Leyendecker JR, Elsayes KM, Gratz BI, Brown JJ. MR cholangiopancreatography: spectrum of pancreatic duct abnormalities. American Journal of Roentgenology. 2002;179(6),1465-1471.
-18. Zyromski NJ, Sandoval JA, Pitt HA, Ladd AP, Fogel EL, Mattar WE, et al. Annular pancreas: dramatic differences between children and adults. Journal of the American College of Surgeons. 2008;206(5),1019-1025.
-19. Jimenez JC, Emil S, Podnos Y, Nguyen N. Annular pancreas in children: a recent decade’s experience. J Pediatr Surg. 2004; 39(11):1654-1657.
-20. Rezvani M, Menias C, Sandrasegaran K, Olpin JD, Elsayes KM, Shaaban AM. Heterotopic pancreas: histopathologic features, imaging findings, and complications. Radiographics. 2017:37(2),484-499.
-21.Vullierme MP, Vilgrain V, Fléjou JF, Zins M, O'Toole D, Ruszniewski P, et al. Cystic dystrophy of the duodenal wall in the heterotopic pancreas: radiopathological correlations. Journal of computer assisted tomography. 2000;24(4),635-643.
-22. Adsay NV, Zamboni G. Paraduodenal pancreatitis: a clinico-pathologically distinct entity unifying “cystic dystrophy of heterotopic pancreas, ”para-duodenal wall cyst,” and “groove pancreatitis”. In Seminars in diagnostic pathology 2004, November (Vol. 21, No. 4, pp. 247-254). WB Saunders.
-23. Cho JS, Shin KS, Kwon ST, Kim JW, Song CJ, Noh S M et al. Heterotopic pancreas in the stomach: CT findings. Radiology. 2000;217(1),139-144.24.
-24. Kim JY, Lee JM, Kim KW, Park HS, Choi JY, Kim SH et al. Ectopic pancreas: CT findings with emphasis on differentiation from small gastrointestinal stromal tumor and leiomyoma. Radiology. 2009;252(1),92-100.
-25. Leyendecker JR, Baginski SG. Complete pancreatic encasement of the portal vein (circumportal pancreas): imaging findings and implications of a rare pancreatic anomaly. Journal of computer assisted tomography. 2008;32(1),61-64.
-26. Tappouni R, Perumpillichira J, Sekala M, Hosseinzadeh K, Clark C, Leyendecker J. Circumportal pancreas: imaging findings in 40 patients. Abdominal imaging. 2015;40,521-530.
-27. Lång K, Lasson Å, Müller M F, Thorlacius H, Toth E, Olsson R. Dorsal agenesis of the pancreas-a rare cause of abdominal pain and insulin-dependent diabetes. Acta Radiologica. 2012;53(1),2-4.
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 iego Haberman, Mariano Volpacchio, Augusto Centellas, Fabrizio Acosta, Karen García, Joaquín Vidal
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
