Restricción alimentaria en la enfermedad celíaca: diagnóstico diferencial entre trastornos de la conducta alimentaria y alimentación desordenada
DOI:
https://doi.org/10.52787/agl.v56i2.653Palabras clave:
Enfermedad celíaca, trastornos de la conducta alimentaria, alimentación desordenada, dieta libre de gluten, anorexia nerviosa, trastorno evitativo/restrictivo de la ingesta alimentariaResumen
La enfermedad celíaca requiere una adherencia estricta a la dieta libre de gluten, lo que puede afectar significativamente las conductas alimentarias y aumentar el riesgo de trastornos de la conducta alimentaria y alimentación desordenada. Si bien resulta clínicamente desafiante, diferenciar estas entidades es fundamental en el contexto de una restricción dietética prescrita. En esta revisión de la literatura, identificamos un mayor riesgo de trastornos de la conducta alimentaria, especialmente de anorexia nerviosa, en personas con enfermedad celíaca, así como conductas de alimentación desordenada, incluyendo restricción excesiva, ansiedad relacionada con los alimentos y evitación social, todas asociadas con una menor calidad de vida. Sin embargo, las herramientas de · M I evaluación actuales no distinguen adecuadamente entre conductas alimentarias patológicas y la adherencia adecuada a una dieta terapéutica prescrita. Aunque se recomienda un abordaje multidisciplinario que incluya apoyo nutricional y de salud mental, aún faltan estrategias terapéuticas específicas basadas en evidencia para la enfermedad. En conjunto, la patología alimentaria en la enfermedad celíaca es frecuente y clínicamente relevante, lo que resalta la necesidad de mejorar su detección y desarrollar herramientas diagnósticas más apropiadas tanto para la práctica clínica como para la investigación.
Citas
-1. Catassi C, Verdu EF, Bai JC, Lionetti E. Coeliac disease. Lancet. 2022;399(10344):2413-2426. DOI:10.1016/S0140-6736(22)00794-2.
-2. Singh P, Arora A, Strand TA, et al. Global Prevalence of Celiac Disease: Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2018;16(6):823-36.e2. DOI:10.1016/j.cgh.2017.06.037.
-3. Hallert C, Grännö C, Hultén S, et al. Living with coeliac disease: controlled study of the burden of illness. Scand J Gastroenterol. 2002;37(1):39-42. DOI:10.1080/003655202753387338.
-4. de Rosa A, Troncone A, Vacca M, Ciacci C. Characteristics and quality of illness behavior in celiac disease. Psychosomatics. 2004;45(4):336-342. DOI:10.1176/appi.psy.45.4.336.
-5. American Psychiatric Association. What are eating disorders? Psychiatry.org. Accessed March 17, 2026. https://www.psychiatry.org/patients-families/eating-disorders/what-are-eating-disorders.
-6. Peters JE, Basnayake C, Hebbard GS, Salzberg MR, Kamm MA. Prevalence of disordered eating in adults with gastrointestinal disorders: A systematic review. Neurogastroenterol Motil. 2022;34(8). DOI:10.1111/nmo.14278.
-7. Staller K, Abber SR, Burton Murray H. The intersection between eating disorders and gastrointestinal disorders: a narrative review and practical guide. Lancet Gastroenterol Hepatol. 2023;8(6):565-578. DOI:10.1016/S2468-1253(22)00351-X.
-8. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 5th ed, text rev (DSM-5-TR). Washington, DC: American Psychiatric Association Publishing; 2022.
-9. Treasure J, Duarte TA, Schmidt U. Eating disorders. Lancet. 2020;395(10227):899-911. DOI:10.1016/S0140-6736(20)30059-3.
-10. Ward ZJ, Bleich SN, Cradock AL, et al. Projected U.S. state-level prevalence of adult obesity and severe obesity. JAMA Netw Open. 2019;2(10). DOI:10.1001/jamanetworkopen.2019.12925.
-11. Schalla MA, Stengel A. Gastrointestinal alterations in anorexia nervosa - A systematic review. Eur Eat Disord Rev. 2019;27(5):447-461. DOI:10.1002/erv.2679.
-12. Zipfel S, Giel KE, Bulik CM, Hay P, Schmidt U. Anorexia nervosa: aetiology, assessment, and treatment. Lancet Psychiatry. 2015;2(12):1099-1111. DOI:10.1016/S2215-0366(15)00356-9.
-13. Academy for Eating Disorders (AED) Medical Care Standards Committee. Eating Disorders: A Guide to Medical Care. 4th ed. Reston, VA: Academy for Eating Disorders; 2021.
-14. Shen Y, Chen B, Zhang H, Shen W, Wu C, Jiang L. Global, regional, and national burden of eating disorders in 204 countries and territories, 1990-2021: findings from the Global Burden of Disease Study 2021. J Eat Disord. 2025;13(1):290. Published 2025 Dec 20. DOI:10.1186/s40337-025-01492-8.
-15. Mars JA, Iqbal A, Rehman A. Binge Eating Disorder. In: StatPearls. StatPearls Publishing; 2026. Updated August 11, 2024. Accessed May 14, 2026. https://www.ncbi.nlm.nih.gov/books/NBK551700/.
-16. Santomauro DF, Melen S, Mitchison D, Vos T, Whiteford H, Ferrari AJ. The hidden burden of eating disorders: an extension of estimates from the Global Burden of Disease Study 2019. Lancet Psychiatry. 2021;8(4):320-328. DOI:10.1016/S2215-0366(21)00040-7.
-17. Udo T, Grilo CM. Psychiatric and medical correlates of DSM-5 eating disorders in a nationally representative sample of adults in the United States. Int J Eat Disord. 2019;52(1):42-50. DOI:10.1002/eat.23004.
-18. Nikniaz Z, Beheshti S, Abbasalizad Farhangi M, Nikniaz L. A systematic review and meta-analysis of the prevalence and odds of eating disorders in patients with celiac disease and vice-versa. Int J Eat Disord. 2021;54(9):1563-1574. DOI:10.1002/eat.23561.
-19. Hansen S, Osler M, Thysen SM, Rumessen JJ, Linneberg A, Kårhus LL. Celiac disease and risk of neuropsychiatric disorders: A nationwide cohort study. Acta Psychiatr Scand. 2023;148(1):60-70. DOI:10.1111/acps.13554.
-20. Butwicka A, Lichtenstein P, Frisén L, Almqvist C, Larsson H, Ludvigsson JF. Celiac Disease Is Associated with Childhood Psychiatric Disorders: A Population-Based Study. J Pediatr. 2017;184:87-93.e1. DOI:10.1016/j.jpeds.2017.01.043.
-21. Lebwohl B, Haggård L, Emilsson L, et al. Psychiatric Disorders in Patients with a Diagnosis of Celiac Disease During Childhood From 1973 to 2016. Clin Gastroenterol Hepatol. 2021;19(10):2093-2101.e13. DOI:10.1016/j.cgh.2020.08.018.
-22. Alkhayyat M, Qapaja T, Aggarwal M, et al. Epidemiology and risk of psychiatric disorders among patients with celiac disease: A population-based national study. J Gastroenterol Hepatol. 2021;36(8):2165-2170. DOI:10.1111/jgh.15437.
-23. Subramanian L, Coo H, Jane A, et al. Celiac Disease and Inflammatory Bowel Disease Are Associated with Increased Risk of Eating Disorders: An Ontario Health Administrative Database Study. Clin Transl Gastroenterol. 2024;15(5). Published 2024 May 1. DOI:10.14309/ctg.0000000000000700.
-24. Mårild K, Størdal K, Bulik CM, et al. Celiac Disease and Anorexia Nervosa: A Nationwide Study. Pediatrics. 2017;139(5). DOI:10.1542/peds.2016-4367.
-25. Hedman A, Breithaupt L, Hübel C, et al. Bidirectional relationship between eating disorders and autoimmune diseases. J Child Psychol Psychiatry. 2019;60(7):803-812. DOI:10.1111/jcpp.12958.
-26. Passananti V, Siniscalchi M, Zingone F, et al. Prevalence of eating disorders in adults with celiac disease. Gastroenterol Res Pract. 2013;2013:491657. DOI:10.1155/2013/491657.
-27. Karwautz A, Wagner G, Berger G, Sinnreich U, Grylli V, Huber WD. Eating pathology in adolescents with celiac disease. Psychosomatics. 2008;49(5):399-406. DOI:10.1176/appi.psy.49.5.399.
-28. Wagner G, Zeiler M, Berger G, et al. Eating Disorders in Adolescents with Celiac Disease: Influence of Personality Characteristics and Coping. Eur Eat Disord Rev. 2015;23(5):361-370. DOI:10.1002/erv.2376.
-29. Babio N, Alcázar M, Castillejo G, et al. Risk of Eating Disorders in Patients With Celiac Disease. J Pediatr Gastroenterol Nutr. 2018;66(1):53-57. DOI:10.1097/MPG.0000000000001648.
-30. Nisihara R, Techy ACM, Staichok C, et al. Prevalence of eating disorders in patients with celiac disease: a comparative study with healthy individuals. Rev Assoc Med Bras (1992). 2024;70(1). Published 2024 Mar 15. DOI:10.1590/1806-9282.20231090.
-31. Bennett A, Bery A, Esposito P, Zickgraf H, Adams DW. Avoidant/Restrictive Food Intake Disorder Characteristics and Prevalence in Adult Celiac Disease Patients. Gastro Hep Adv. 2022;1(3):321-327. Published 2022 Mar 30. DOI:10.1016/j.gastha.2022.01.002.
-32. Rabiee R, Mahdavi R, Shirmohammadi M, Nikniaz Z. Eating disorders, body image dissatisfaction and their association with gluten-free diet adherence among patients with celiac disease. BMC Nutr. 2024;10(1):100. Published 2024 Jul 18. DOI:10.1186/s40795-024-00910-5.
-33. Litmanen J, Fröjd S, Marttunen M, Isomaa R, Kaltiala-Heino R. Are eating disorders and their symptoms increasing in prevalence among adolescent population? Nord J Psychiatry. 2017;71(1):61-66. DOI:10.1080/08039488.2016.1224272.
-34. Morgan JF, Reid F, Lacey JH. The SCOFF questionnaire: assessment of a new screening tool for eating disorders. BMJ. 1999;319(7223):1467-1468. DOI:10.1136/bmj.319.7223.1467.
-35. National Institute for Health and Care Excellence. Eating disorders: recognition and treatment (NG69). NICE. Published May 23, 2017. Exceptional surveillance updated 2024. Accessed March 17, 2026. https://www.nice.org.uk/guidance/ng69.
-36. Fairburn CG, Cooper Z, O’Connor ME. Eating Disorder Examination. Edition 17.0D. CBT-E website. Published January 2014. Accessed May 14, 2026. https://www.cbte.co/for-professionals/measures/.
-37. Sysko R, Glasofer DR, Hildebrandt T, et al. The eating disorder assessment for DSM-5 (EDA-5): development and validation of a structured interview for feeding and eating disorders. Int J Eat Disord. 2015;48(5):452-463. DOI:10.1002/eat.22388.
-38. Garner DM. Eating Disorder Inventory-3: Professional Manual. Psychological Assessment Resources; 2004.
-39. Schaefer LM, Crosby RD, Machado PPP. A systematic review of instruments for the assessment of eating disorders among adults. Curr Opin Psychiatry. 2021;34(6):543-562. DOI:10.1097/YCO.0000000000000746.
-40. Crone C, Fochtmann LJ, Attia E, et al. The American Psychiatric Association practice guideline for the treatment of patients with eating disorders. Am J Psychiatry. 2023;180(2):167-171. DOI:10.1176/appi.ajp.23180001.
-41. Kambanis PE, Thomas JJ. Assessment and Treatment of Avoidant/Restrictive Food Intake Disorder. Curr Psychiatry Rep. 2023;25(2):53-64. DOI:10.1007/s11920-022-01404-6.
-42. Ramirez Z, Gunturu S. Avoidant Restrictive Food Intake Disorder. In: StatPearls. StatPearls Publishing; 2024. Updated May 1, 2024.
-43. Di Cara M, Rizzo C, Corallo F, et al. Avoidant Restrictive Food Intake Disorder: A Narrative Review of Types and Characteristics of Therapeutic Interventions. Children (Basel). 2023;10(8):1297. Published 2023 Jul 28. DOI:10.3390/children10081297.
-44. Coburn S, Germone M, McGarva J, Taft T. Psychological Considerations for Food Intolerances: Celiac Sprue, Eosinophilic Esophagitis, and Non-Celiac Gluten Sensitivity. Gastroenterol Clin North Am. 2022;51(4):753-764. DOI:10.1016/j.gtc.2022.07.003.
-45. Satherley RM, Higgs S, Howard R. Disordered eating patterns in coeliac disease: a framework analysis. J Hum Nutr Diet. 2017;30(6):724-736. DOI:10.1111/jhn.12475.
-46. Simons M, McGarva J, Doerfler B, et al. Food-related quality of life driven by hypervigilance and anxiety around eating in organic gastrointestinal conditions. J Hum Nutr Diet. 2024;37(6):1505-1515. DOI:10.1111/jhn.13358.
-47. Lee AR, Zybert P, Chen Z, et al. Food avoidance beyond the gluten-free diet and the association with quality of life and eating attitudes and behaviors in adults with celiac disease. Nutrients. 2024;16(19):3411. DOI:10.3390/nu16193411.
-48. Lebovits J, Lee AR, Ciaccio EJ, et al. Impact of Celiac Disease on Dating. Dig Dis Sci. 2022;67(11):5158-5167. DOI:10.1007/s10620-022-07548-y.
-49. Zysk W, Glabska D, Guzek D. Food Neophobia in Celiac Disease and Other Gluten-Free Diet Individuals. Nutrients. 2019;11(8):1762. Published 2019 Jul 31. DOI:10.3390/nu11081762.
-50. Leffler DA, Dennis M, Edwards George JB, Kelly CP. The interaction between eating disorders and celiac disease: an exploration of 10 cases. Eur J Gastroenterol Hepatol. 2007;19(3):251-255. DOI:10.1097/MEG.0b013e328012db37.
-51. Gholmie Y, Lee AR, Satherley RM, et al. Maladaptive Food Attitudes and Behaviors in Individuals with Celiac Disease and Their Association with Quality of Life. Dig Dis Sci. 2023;68(7):2899-2907. DOI:10.1007/s10620-023-07912-6.
-52. Cadenhead JW, Lee AR, Nguyen TTT, Lebwohl B, Green PHR, Wolf RL. Dietary Adherence to Recommendations among a Cohort of Adults and Teens with Celiac Disease Maintaining a Gluten-Free Diet Compared to a Nationally Representative Sample: A Cross-Sectional Study. Nutrients. 2024;16(18):3067. Published 2024 Sep 11. DOI:10.3390/nu16183067.
-53. Wolf RL, Lebwohl B, Lee AR, et al. Hypervigilance to a Gluten-Free Diet and Decreased Quality of Life in Teenagers and Adults with Celiac Disease. Dig Dis Sci. 2018;63(6):1438-1448. DOI:10.1007/s10620-018-4936-4.
-54. Rajani S, Sawyer-Bennett J, Shirton L, et al. Patient and parent satisfaction with a dietitian- and nurse-led celiac disease clinic for children at the Stollery Children's Hospital, Edmonton, Alberta. Can J Gastroenterol. 2013;27(8):463-466. DOI:10.1155/2013/537160.
-55. Mulder CJJ, Elli L, Lebwohl B, et al. Follow-Up of Celiac Disease in Adults: "When, What, Who, and Where". Nutrients. 2023;15(9):2048. Published 2023 Apr 24. DOI:10.3390/nu15092048.
-56. Riehl ME, Scarlata K. Understanding disordered eating risks in patients with gastrointestinal conditions. J Acad Nutr Diet. 2022;122(3):491-499. DOI:10.1016/j.jand.2021.03.001.
-57. Ciao AC, Loth K, Neumark-Sztainer D. Preventing eating disorder pathology: common and unique features of successful eating disorders prevention programs. Curr Psychiatry Rep. 2014;16(7):453. DOI:10.1007/s11920-014-0453-0.
-58. Quick VM, Byrd-Bredbenner C, Neumark-Sztainer D. Chronic illness and disordered eating: a discussion of the literature. Adv Nutr. 2013;4(3):277-286. DOI:10.3945/an.112.003608.
-59. Cotton MA, Ball C, Robinson P. Four simple questions can help screen for eating disorders. J Gen Intern Med. 2003;18(1):53-56. DOI:10.1046/j.1525-1497.2003.20374.x.
-60. Satherley RM, Howard R, Higgs S. Development and validation of the Coeliac Disease Food Attitudes and Behaviours Scale. Gastroenterol Res Pract. 2018;2018:6930269. DOI:10.1155/2018/6930269.
-61. Solmi M, Radua J, Olivola M, et al. Age at onset of mental disorders worldwide: large-scale meta-analysis of 192 epidemiological studies. Mol Psychiatry. 2022;27:281-295. DOI:10.1038/s41380-021-01161-7.
-62. Rowen K, Solomon P, Tebbett-Mock A. Psychosocial predictors of disordered eating in adolescents with celiac disease: a cross-sectional study. Child Health Care. Published online 2026. DOI:10.1080/02739615.2026.2626386.
-63. Lee AR, Lebwohl B, Lebovits J, Wolf RL, Ciaccio EJ, Green PHR. Factors associated with maladaptive eating behaviors, social anxiety, and quality of life in adults with celiac disease. Nutrients. 2021;13(12):4494. DOI:10.3390/nu13124494.
-64. Wei Y, Wang Y, Yuan Y, Chen J. Celiac disease, gluten-free diet, and eating disorders: from bench to bedside. Foods. 2025;14(1):74. DOI:10.3390/foods14010074.
-65. Bennett A, Bery A, Esposito P, Zickgraf H, Adams DW. Avoidant/restrictive food intake disorder characteristics and prevalence in adult celiac disease patients. Gastro Hep Adv. 2022;1(3):321-327. DOI:10.1016/j.gastha.2022.01.002.
-66. Jamieson JA, Weir M, Gougeon L. Canadian packaged gluten-free foods are less nutritious than their regular gluten-containing counterparts. PeerJ. 2018;6. DOI:10.7717/peerj.5875.
-67. Roncoroni L, Bascuñán KA, Doneda L, et al. A low FODMAP gluten-free diet improves functional gastrointestinal disorders and overall mental health of celiac disease patients: a randomized controlled trial. Nutrients. 2018;10(8):1023. DOI:10.3390/nu10081023.
-68. Kaul R, Jansson-Knodell C, Simons ML, Weekley K, Gardinier D, Rubio-Tapia A. Avoidant/restrictive food intake disorder in celiac disease. Nutrients. 2025;17:3197. DOI:10.3390/nu17203197.
-69. Kleiman SC, Watson HJ, Bulik-Sullivan EC, et al. The intestinal microbiota in anorexia nervosa. Psychosom Med. 2015;77(9):969-981. DOI:10.1097/PSY.0000000000000247.
-70. Zingone F, Swift GL, Card TR, Sanders DS, Ludvigsson JF, Bai JC. Psychological morbidity of celiac disease: a review of the literature. United European Gastroenterol J. 2015;3(2):136-145. DOI:10.1177/2050640614560786.
-71. Melton SL, Knowles SR, Gwee KA, Gibson PR, Tuck CJ, Day AS. Diet Stacking - An Expanding Challenge for Gastroenterologists and Dietitians in Managing Chronic Gastrointestinal Disorders. JGH Open. 2025;9(12).
-72. Lee AR, Dennis M, Lebovits J, Welstead L, Verma R, Therrien A, Lebwohl B. Dietary assessments in individuals living with coeliac disease: key considerations. J Hum Nutr Diet. 2025;38(1).
-73. Blom JJ, Gidrewicz D, Turner J, Duerksen DR, Pinto-Sánchez MI. Diagnosis and management of celiac disease. CMAJ. 2025;197(38). DOI:10.1503/cmaj.230091.
-74. Mond JM, Hay PJ, Rodgers B, Owen C, Beumont PJ. Validity of the Eating Disorder Examination Questionnaire (EDE-Q) in screening for eating disorders in community samples. Behav Res Ther. 2004;42(5):551-567. DOI:10.1016/S0005-7967(03)00161-X.
-75. Open Resources for Nursing. Chapter 13: Eating Disorders. In: Ernstmeyer K, Christman E, eds. Nursing: Mental Health and Community Concepts. Chippewa Valley Technical College; 2022. Accessed May 14, 2026. https://www.ncbi.nlm.nih.gov/books/NBK590029/.
-76. Hay P. Current approach to eating disorders: a clinical update. Intern Med J. 2020;50(1):24-29. DOI:10.1111/imj.14691.
-77. Peschel SKV, Sigrist C, Voss C, et al. Subclinical patterns of disordered eating behaviors in the daily life of adolescents and young adults from the general population. Child Adolesc Psychiatry Ment Health. 2024;18(1):69. Published 2024 Jun 6. DOI:10.1186/s13034-024-00752-w.
-78. Reba-Harrelson L, Von Holle A, Hamer RM, Swann R, Reyes ML, Bulik CM. Patterns and prevalence of disordered eating and weight control behaviors in women ages 25-45. Eat Weight Disord. 2009;14(4). DOI:10.1007/BF03325116.
Descargas
Publicado
Cómo citar
Número
Sección
Licencia
Derechos de autor 2026 C V Noejovich, N Bhola, M P Temprano, D Armstrong, María Inés Pinto-Sanchez

Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-CompartirIgual 4.0.










